Per: Taiana de Sousa Matos (UNIVERSIDADE FEDERAL DO PARÁ), Marcos Vinícius da Silva Paula (UNIVERSIDADE FEDERAL DO PARÁ), Damares da Cruz Barbosa Nascimento (UNIVERSIDADE FEDERAL DO PARÁ), Alisson Clay Rios da Silva (UNIVERSIDADE FEDERAL DO PARÁ), Carlos Alberto Brito da Silva Júnior (UNIVERSIDADE FEDERAL DO PARÁ), Severino Alves Junior (UNIVERSIDADE FEDERAL DE PERNAMBUCO), Verônica Scarpini Candido (UNIVERSIDADE FEDERAL DO PARÁ)
Abstract:
The exploration of new wound treatments represents a significant advance in the area of tissue engineering. In this sense, films made of poly(vinyl alcohol) (PVA) and chitosan (CS) containing copaiba oil emulsion and silver nanoparticles show promise as dressings. These films seek, through a synergistic effect, to create biomaterials with a wide range of biological actions, capable of accelerating wound repair and healing. The research focused on the production and characterization of PVA/CS films in proportions of 0.2:0.8 (m/v), respectively, with 0.1% and 0.5% (v/v) of copaiba oil and 10 mL of silver nanoparticles, using the casting method, aiming for their potential use in wounds. The silver nanoparticle and the copaiba oil emulsion were analyzed using the UV/Vis (UV-Visible) technique. In general, most films presented excellent optical transparency. Based on the evaluation of the results, the BP 0.5% AgNPS (v/v) films proved to be more suitable for application compared to the other samples.